AMS Series
Steam-and-air mixture terminal sterilizer
Terminal sterilization for injectable solutions and other pharmaceutical products that must leave the load dry and ready for handling. The steam-and-air mixture sterilization process protects pressure- and heat-sensitive materials from deformation or damage. Conveyors and robotic interfaces support semi- or fully automated workflows.
Typical loads
Suitable for terminal sterilization of a wide range of items, including:
- SVP (liquids in ampoules, vials, syringes, cartridges)
- LVP (liquids in glass bottles, BFS, FFS)
- Contact lenses in blister packaging
- Blood plasma pasteurization
Sanitary GMP construction
Built for sanitary application in regulated environments: fully drainable designs, non-retentive surfaces and 316L stainless steel with a smooth finish. Welds are ground flush and fabrication can be documented in a complete logbook. Process-contact materials with EN 10204 traceability and USP Class VI compliant elastomers.
Steam-and-air sterilization process
- Pure steam heats the load inside the chamber
- Sterile compressed air is injected to balance product internal pressure during heating and cooling
- Fans circulate the steam-and-air mixture to keep temperature distribution uniform
- Side-mounted cooling coils provide rapid, controlled cooling at the end of the cycle
- The load is completely dry at the end of the cycle
Workflow optimization and load handling
SteelcoBelimed supports productivity and quality through semi-automatic or fully automated loading and unloading systems, including conveyors and robot integration. AISI 316L stainless-steel racks with guided positioning and push-pull devices support consistent loading, improved ergonomics and efficient operation.
Features
Optimal temperature distribution
A centrifugal fan recirculates the steam-and-air mixture around the load, guided by baffle plates, to maintain a uniform temperature. A mechanical coupling transfers power from an external motor to support high airflow and fast heat exchange.
Rapid cooling
Stainless steel cooling coils on the chamber sides speed up load cooling after sterilization. The fan recirculates air between the load and the coils for controlled, repeatable cooling.
Cycle development and validation support
We develop cycles around your loads and acceptance criteria, then document them in a qualification package aligned to your project scope. Risk-based cycle definition, mapping and test support help you reach a robust, repeatable process sooner.
Non-proprietary components
The equipment is manufactured with proven, globally available, industry-standard components rather than proprietary parts. Original spare parts can be sourced through SteelcoBelimed with appropriate documentation and traceability or directly from original manufacturers.
Services
Integrated automation – ready for your architecture
SteelcoBelimed automation can integrate into Siemens, Rockwell and Proficy iFix environments. The platform combines modern technologies with tested, validated solutions developed in accordance with GAMP 5, supporting data integrity and compliance expectations.
SteelcoBelimed equipment for pharmaceutical applications is designed and manufactured in accordance with cGMP principles and within an ISO 9001–certified quality system. All systems are developed to meet applicable international pharmaceutical regulations (FDA, EU GMP), as well as relevant electrical, EMC and safety requirements.
Chamber volume
16 standard chamber sizes: 830 to 25,000 liters / 30 to 880 cu ft
Custom dimensions available upon request
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