Aseptic transfer for Closure Processing System
Sterile transfer from processing to point of use
A wide range of aseptic discharge solutions for pharmaceutical closures, from ported bags and transfer containers to direct pneumatic transport and thermo-sealable bags, ensuring controlled sterile transfer to the filling line.
Where sterile transfer becomes critical
After washing and sterilization, closures must be transferred from the processing equipment to their point of use, often a filling line under isolator located at a distance. Maintaining sterility during this step is essential.
The revised EU GMP Annex 1 further strengthens this requirement by stating that components should be sterilized in their primary packaging where applicable. This adds complexity to discharge and transport concepts for facilities processing closures in house.
A panel of discharge and transfer solutions
SteelcoBelimed provides a range of standard discharge and transfer options to match different facility layouts and contamination control strategies. Each solution is designed to preserve aseptic conditions and support new Annex 1 expectations regarding primary packaging and contamination control.
Sterile bag transfer
Transfer via single-use sterile bags fitted with a Rapid Transfer Port
Vessel transfer
Transfer via sterilizable stainless-steel mobile vessel fitted with a Rapid Transfer Port
Direct transfer
Direct aseptic transfer via piping system connecting to the filling line stopper bowl
Bag transfer for RTS
Discharge into thermo-sealable bags, suitable for producers of Ready-To-Sterilize closures
Integrated and compliant by design
Sterile discharge is not limited to the equipment outlet. It must integrate with the facility’s material flow, isolator systems and filling lines. SteelcoBelimed solutions are engineered to ensure seamless transfer between sterilization, transport and use.
Whether for pharmaceutical manufacturers processing closures in house or suppliers delivering Ready-To-Sterilize closures, the result is a discharge concept tailored to each case, supporting sterility assurance and compliance with the revised EU GMP Annex 1.
Whether for pharmaceutical manufacturers processing closures in house or suppliers delivering Ready-To-Sterilize closures, the result is a discharge concept tailored to each case, supporting sterility assurance and compliance with the revised EU GMP Annex 1.
